Forming and waking dormant cells: The ppGpp ribosome dimerization persister model
Procaryotes starve and face myriad stresses.The bulk population actively resists the stress, but a small population weathers the stress by entering a resting stage known as persistence.No mutations occur, and so persisters behave like wild-type cells upon removal of the stress and regrowth; hence, persisters are phenotypic variants.In contrast, res